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Murine Lifespan Studies
Research on aging has often been focused on individual diseases. Using pre-aged mice, however, we can investigate the complex process that is aging as a whole. Lifespan studies investigate the effect of an intervention or a series of interventions on longevity and health span.
Pre-aged C57BL/6 and HET3 mice are readily available. These are some of the most commonly used animal models for the study of lifespan and health span interventions. Using mice, we can examine interventions across a lifespan that is relatively short to assess effectiveness more efficiently.
Body weight and condition
Body weight monitoring and body condition scoring is an imperative non-invasive measure of health in aged animals.
Hematology
Blood chemistries, complete blood counts and flow cytometry on peripheral blood can help monitor health progression over time.
Behavioral Assessments
Ichor offers a host of assays to evaluate health span. This includes several behavioral tests as well as metrics to assess frailty.
Lifespan and Biomarker Cohorts
Aged mice can be more sensitive to manipulation. Let us help you decide the study design that best fits your needs.
Histology
Endpoint analyses of tissues for markers of neoplasms and fibrosis.
Inbred or outbred
We are familiar with working with both the inbred C57BL6 and the genetically diverse HET3.
Longevity, Lifespan, & Healthspan
Rooted in the Lifespan space, Ichor Life Sciences is your premier partner for all longevity, lifespan and healthspan studies. Husbandry consideration for aged animals can be very different from that of young animals. Our knowledge and experience with these models allow us to best care for these animals at all stages of lifespan and provide them with the most compassionate care and humane endpoint without compromising study integrity.
Compassionate care for better data
Enriched environment in every cage
Our animals are provided with several types of enrichment to enhance their natural behaviors. This is particularly important for studies that can be years in duration.
Enhanced veterinary attention and care
With unmatched attention to detail, our staff can identify health issues as they arise to offer supplemental supportive care as needed and compassionate yet scientifically-sound endpoints.
Frequently Asked Questions
We are experts in designing and implementing small and large-scale lifespan studies. Let our vast experience guide your next foray into life extension.