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Kinetics of the multitasking high-affinity Win binding site of WDR5 in restricted and unrestricted conditions (2021)
Using real-time binding measurements in a high-throughput setting, we identified the kinetic fingerprint of transient associations between WDR5 and 14-residue WDR5 interaction (Win) motif peptides of each SET1 protein (SET1Win).
We dissected the molecular differences between a weak and a strong SIRT6 protein and identified five amino acid residues that are fully responsible for their differential activities, demonstrating that DSB repair and SIRT6 have been optimized during the evolution of longevity.
Ichor Publishes Article Unraveling Evolutionary Mechanisms of Phase Separation Proteins in Extreme Microorganisms
Ichor Publishes Article Unraveling Evolutionary Mechanisms of Phase Separation Proteins in Extreme Microorganisms Lafayette, N.Y. – September 8, 2022 – Ichor Life
LENTO BIO RAISES $680,000 IN OVERSUBSCRIBED SEED ROUND LED BY ICHOR LIFE SCIENCES Potsdam, N.Y. – September 6, 2022 – Lento Bio,
ICHOR LIFE SCIENCES INVESTS $1.5 MILLION IN MITOCHEM THERAPEUTICS FOR OCULAR AGING DISEASE RESEARCH LaFayette, N.Y. – August 11, 2022 – Ichor