Biophysical Assays

Biophysical assays find extensive applications in various areas of research and industry, playing a crucial role understanding biological interactions and are extensively used in drug discovery, structural biology, and biotechnology, some of the key applications of biophysical assays include:

Target Validation:

Prior to investing resources in developing drugs to target a specific biomolecule, confirmation of the chose target is needed, in order to know if it is relevant and likely to produce the desired therapeutic effects. Biophysical assays are key in the validation process, through providing insights into the interactions and properties of the target biomolecule.

Lead Optimization:

Optimisation of lead compounds is completed via biophysical assays, the study of binding kinetics allows crucial decisions on chemical modifications, that enhances drug potency, selectivity, and stability.

Drug Discovery:

Biophysical assays are utilized for identifying and validating potential drug targets, prioritizing lead compounds, and optimising interaction with target biomolecules, accelerating the drug discovery process, and increasing the chance of discovering effective and safe therapeutics.

Mechanism of Action:

Through our biophysical assays, you can investigate the molecular pathways involved in drug-target interactions, enabling the optimization of the drug’s safety and efficacy, along with how it exerts therapeutic effects.

Molecular Interaction Mapping:

Access to biomolecular techniques such as Nuclear Magnetic Resonance (NMR) and X-Ray Crystallography, which map molecular interactions at an atomic resolution, this provides detailed structural information, guiding the design of small molecules or peptides that disrupt specific interactions.