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Formulation Services
Are you ready to move from compound to a study ready dosing formulation with an experienced preclinical CRO? Ichor Life Sciences provides formulation services designed to support dosing, reproducible study execution, and development decisions.
A formulation that performs well on paper still has to work in the realities of a preclinical study. At Ichor, our scientists approach formulation development with the intended route of administration, dosing volume, concentration, compound properties, study duration, and downstream endpoints in mind.
Our formulation services help support programs that require solutions for solubility, stability, homogeneity, concentration, and dose preparation. Our scientist will work with your team to establish a formulation strategy that is appropriate for the investigational product of interest.
Custom Preclinical Formulation Development
Formulation Screening
Evaluate candidate vehicles, excipients, concentrations, and preparation approaches to identify practical formulations for preclinical dosing.
Solubility Optimization
Assess formulation approaches intended to improve compound solubility and achieve target dosing concentrations.
Suspension & Solution Development
Develop solutions and/or suspension formulations based on compound characteristics and study requirements.
Vehicle & Excipient Selection
Select vehicles and excipients based on route, species, dosing frequency, tolerability, and experimental objectives.
Dose Formulation Preparation
Prepare formulations based on defined procedures to ensure control across dosing days and treatment groups.
Study Integration
Cross formulation development with Ichor’s in vivo pharmacology, PK/PD, toxicology, and bioanalytical capabilities.
Formulations Designed for Preclinical Programs
Ichor’s formulation services are intended to support development programs where dosing feasibility is essential for interpreting study results. Project requirements vary by compound, modality, species, and route, so formulation plans are developed around the specific needs of each program rather than a one-size-fits-all workflow.
Depending on your project, formulation development may support common preclinical administration routes such as oral, intravenous, subcutaneous, intraperitoneal, topical, and other study-specific routes. Specialized routes will be discussed with our scientific team during study planning.
Why Integrate Formulation and Preclinical Study Execution?
With Ichor, you can keep formulation development close to the same team executing the study! This will help reduce the mishaps associated with handoffs and ensure that preparation procedures align with dosing requirements. For clients working with Ichor for in vivo work, the same project can connect formulation planning with pharmacology, PK/PD, toxicology, histology, and bioanalysis.
This program based model makes our formulation services especially useful for teams looking for a CRO partner capable of supporting both formulation strategy and the downstream preclinical work that depends on it.
Frequently Asked Questions
Answers to some of the most common questions about our ophthalmic cro service offerings.