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Optic Nerve Crush Model (ONC)
We would like to partner with you and your products' neuroprotection capabilities to bring patients relief from glaucoma, a devastating disease resulting in the loss of vision from increased pressure on the optic nerve. Our rodent ONC model mimics the onset of disease and the nerve damage associated with Glaucoma.
We provide the ability to track disease progression after induction of disease by utilizing optical coherence tomography (OCT), measuring full retinal thickness, the retinal ganglion cell (RGC) layer and nerve fiber layer (RNFL) in real time.
In conjunction with OCT we use electroretinography (ERG) to test retinal functionality. Upon the conclusion of the study, we use histopathology to assess the condition of the retinal ganglion cells and potential protection from your product to RGC and RNFL.
Optical Coherence Tomography
High quality retinal scanning using the Lecia® SD-OCT allows for accurate retinal thickness measurements of distinct retinal layers.
Electroretinography
Our lab uses a proprietary ERG system in collaboration with Cornell University to produce the most accurate ERGs.
Microinfusion Injection Delivery
Confirmation fundus images of each injection procedure that ensures proper delivery of treatment.