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Acute Toxicology and Dose Finding Studies
Performing a dose range finding study followed by acute toxicity studies are critical components of a successful drug development pipeline. Learn more about how Ichor Life Sciences can support your project during this crucial stage!
We offer full-service dose range finding and acute toxicity study support, from discovery to pivotal IND-enabling workflows.
Dose Range Finding Study
Ichor will help you identify the appropriate dosing regime to ensure smooth progress through regulatory submission.
Acute Toxicity Studies
Short and simple toxicology testing reveals potential adverse events and unexpected findings early in your pipeline.
Repeat Dose Tox
Sustained administration of compounds over time more accurately reflects clinical application and will help predict results in humans.
Capabilities and Services Summary
High Animal Welfare Standard
Our technical and veterinary team adhere to the highest standards for animal care and welfare. Not only is our vivarium an AAALAC accredited facility with an in-house IACUC, but our team goes the extra mile to give the animals the best level of care. We have a robust positive reinforcement training program as well as industry-leading housing and enrichment standards.
In-House Capabilities
Ichor serves as a one-stop-shop for many in vivo study needs, and we use the most state-of-the-art equipment for the work we perform. Our team can assess neurobehavioral endpoints, perform almost every blood collection or dosing technique, as well as a myriad of ophthalmology techniques, and more. You can be confident you’re getting the best there is to offer.
Experts in the Unconventional
Ichor is your ideal partner for unconventional ideas and studies. Before spending exorbitant amounts of money on a GLP study, consider partnering with our team to run a DRF or exploratory study so you can begin your large-scale GLP studies with confidence.
Frequently Asked Questions
Optimal preclinical study design is essential for successful drug development. Let our vast experience guide your thinking.
Non-GLP dose range finding studies set the stage for all future work. A systematic approach is taken to determine the ideal therapeutic range while minimizing adverse events.
A dose range finding study is a prerequisite for further preclinical development. Single and repeat dose acute toxicity studies identify adverse events and establishes a relationship between dose level over time.
Generating information from these studies is crucial for initiating GLP studies. This is the chance to explore the basic pharmacological properties of your drug and maximize the likelihood of success in future studies, saving invaluable time and money.
GLP studies are significantly more expensive to repeat than these initial exploratory studies. These studies can be repeated and refined to arrive at the optimal study design for GLP work to be presented to the FDA, EMA, etc.
From initial contact to final study reporting, you can have reliable data in your hands within 4-6 weeks.