Skip to content
PK/TK Models
Ichor Life Sciences is your ideal partner for reliable PK/TK studies and data. We combine our technical in-life expertise with advanced bioanalysis and PK/TK data evaluation to provide our clients with the highest quality deliverables, from dose to report.
Core Capabilities & Services
Pharmacokinetic (PK) Services
- Single-dose and repeat-dose PK
- Plasma and tissue distribution studies
- Route comparison studies
- PK data analysis
Toxicokinetic (TK) Services
- TK sampling within toxicity studies
- Bioanalytical method development (LC-MS/MS, GC-MS/MS, qPCR)
- TK data analysis
Data & Deliverables
- Concentration-time profiles
- PK parameters tables
- non-compartmental and compartmental modeling with WinNonlin
- TK data summary tables
- Draft and final reports
Administration and Collection Techniques
Our technical staff are experienced in a wide-range of administration routes and sample collection techniques. Serial and terminal sampling are available, and we work to ensure the highest quality plasma and tissue PK/TK samples with minimal stress to the animals.
| Category | Techniques / Routes |
|---|---|
| Blood Collection Techniques |
|
| Dose Administration Routes |
|
Investigative Studies
Our preclinical PK/TK research team is ready to help you further investigate the tolerability and toxicity of your compound. By partnering with Ichor Life Sciences, you’re choosing a capable and dedicated team to help with your investigative and nonGLP studies allowing you to enter larger-scale projects with confidence.
Capabilities and Services Summary
High Animal Welfare Standards
Our technical and veterinary team adhere to the highest standards for animal care and welfare. Not only is our vivarium an AAALAC accredited facility with an in-house IACUC, but our team goes the extra mile to give the animals the best level of care. We have a robust positive reinforcement training program as well as industry-leading housing and enrichment standards.
In-House Capabilities
Ichor serves as a one-stop-shop for many in vivo study needs, and we use the most state-of-the-art equipment for the work we perform. Our team can assess neurobehavioral endpoints, perform almost every blood collection or dosing technique, as well as a myriad of ophthalmology techniques, and more. You can be confident you’re getting the best there is to offer.
Experts in the Unconventional
Ichor is your ideal partner for unconventional ideas and studies. Before spending exorbitant amounts of money on a GLP study, consider partnering with our team to run a DRF or exploratory study so you can begin your large-scale GLP studies with confidence.