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MOC2 Mouse Model
MOC2 is a highly aggressive variant of oral cavity squamous cell carcinoma, a subset of head and neck and cancer. MOC1 and MCO2 were derived alongside each other, however they have different growth phenotypes. MOC2 exhibits an aggressive growth phenotype and immuno-suppressive environment which makes it ideal for research.
We have characterized the MOC2 mouse model of oral cavity squamous cell carcinoma expressed as a flank model in C57BL/6 mice allowing for the exploration of new therapeutic agents, immune responses, and histological endpoints on primary tumors and metastases.
Fast Growing and Reproducible
The fast-growing tumors present in our MOC2 syngeneic model allow for efficient and reproducible analysis of therapeutics.
Metastatic Potential
Metastases to the lymph nodes and lungs are common, making it a valuable model for studying cancer metastasis.
Murine Oral Squamous Cell Carcinoma
Commonly Requested Endpoints
Histopathology
Our customizable histopathological analysis can help evaluate tumor microenvironments, track tumor progression and metastases and inform treatment decisions.
Flow Cytometry
Our flow cytometry expertise can help characterize tumor-infiltration T lymphocytes, identity immune biomarkers, and so much more.