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Recombinant AAV is used as a versatile platform for gene delivery in both in vitro and in vivo applications, offering stable expression in dividing and non-dividing cells.
With a packaging capacity of ~4.5 kb and serotype-specific tropism, AAV vectors are an indispensable tool for gene therapy research, functional screening, and preclinical studies.
Applications We Support
In vitro gene expression studies
Cell painting facilitates the tracking of cellular receptors. Differential permeabilization provides information on receptor surface presentation or internalization.
shRNA delivery and downstream validation
Use custom AAV-shRNA to knock down target genes, then validate transcript and protein-level depletion by qPCR, immunoblotting, or imaging.
Functional Screening
Produce custom AAV with us to support your downstream functional assays—leveraging molecular and imaging-based readouts. Crude and small-scale AAV formats are available for rapid, in vitro optimization.
Preclinical Proof-of-Concept Studies
Select AAV serotypes with defined tissue tropism (e.g., AAV8 for liver, AAV9 for CNS or muscle) to evaluate in vivo gene delivery, expression, and therapeutic activity.
Our AAV Packaging Pipeline
From plasmid transfection to purification and full QC, our streamlined pipeline delivers custom AAV vectors ready for your next in vitro or in vivo experiment.
We bring deep expertise in gene design, molecular cloning, and viral vector engineering to streamline your AAV project. Choose from multiple serotypes for packaging in mammalian cells, with our standard deliverable - purified virus and quantified viral titer via ITR-based qPCR, capsid ELISA, and optional sterility testing.
Frequently Asked Questions
~4.7 kb including promoters, coding regions, and regulatory elements.
AAV2, AAV6, AAV8, AAV9, and others based on project needs.
We use a combination of ITR-based qPCR and optional capsid ELISA for accurate genome and particle counts.