Uveitis Model

Evaluate your investigational product using our established Experimental Autoimmune Uveitis (EAU) and Endotoxin-Induced Uveitis (EIU) models. Does your program require custom solutions? Inquire about our custom services.

Experimental Autoimmune Uveitis Model (EAU)

We immunize with IRBP+CFA for disease induction with a validated positive control. Select from a variety of analytical endpoints.

Endotoxin Induced Uveitis Model (EIU)

We deliver LPS by IVT injections unlike other models that use systemic approaches to provide more robust results and avoid systemic adverse effects.

Featured Capabilities

Our veterinary ophthalmology team supports uveitis research studies with a variety of solutions for clients.

Anterior Segment Imaging

Topical Drug Delivery

Inflammatory Cytokine & Chemokine Analysis

Microinfusion Injection Delivery

Histology Services

Uveitis Model Clinical Scoring

Endotoxin-Induced Uveitis (EIU) Model

This figure shows representative clinical pathology scoring of the EIU model. Uveitis in this model is attenuated by administration of a steroid.

Experimental Autoimmune Uveitis (EAU) Model

This graph illustrates the ability of IRBP+CFA to induce uveitis and FTY-720 suppressing the inflammatory response. Here we show that delivery of LPS is just as effective at disease induction as systemic foot-pad injections.

From individual studies to programs, what are your project needs?

Accelerate your uveitis research by speaking with our experts.

Uveitis Models